![]() The development of polymethylpentene (PMP) hollow fiber membrane lung oxygenator (membrane lung, ML) was likely the most important technical improvement in this field. The use of extracorporeal membrane oxygenation (ECMO) for the management of the most severe cases of acute respiratory failure is becoming increasingly widespread, thanks also to technological advances. ML oxygenation performance was marginally affected. The RM improved ML CO 2 removal substantially, albeit temporarily. The beneficial effects on ML performances due to the RM gradually diminished and waned over a 6-h interval after the RM. ![]() Furthermore, a subset of 5 RMs was evaluated on a 6-h time frame. Conversely, RM did not improve ML O 2 transfer (155 ± 31 and 158 ± 31 ml/min before and after RM, respectively). Short-term (15 min) effects of 20 RMs were assessed. The purpose of this study was to evaluate the effects on ML gas exchange of a recruitment maneuver (RM) based on a brief increase in GF, during veno-venous ECMO support. ![]() Increasing sweep gas flow (GF) could remove such fluid. ![]() Condensation and trapping of water vapor inside ML hollow fibers might affect ML performances as well. ML deterioration is related to protein deposit and clot formation. ![]() Gas exchange capabilities of polymethylpentene membrane lungs (MLs) worsen over time. ![]()
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